In an interview to Esquire, the 53-year-old 'Milk' actor, who is in a relationship with Charlize Theron, said that it has made him realise that he hasn't "been happy in a single relationship" before, reported E! online.
"I'm surprised to be in love. Lot of reasons. 53 years old plus finally beginning to figure out why you haven't been happy in a single relationship?
"It could seem too late. But to run into somebody now who you care about is a much passionate, deeper, truer and - god! - a much happier feeling," Penn said.
Penn was previously married to Madonna for four years in the 1980s and to Robin Wright for 13 years until their divorce was finalised in 2010.
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On the possibility of marrying for a third time, he said: "Yes, I'd get married again. You say I've been married twice before but I've been married under circumstances where I was less informed than I am today, so I wouldn't even consider a third marriage, I'd consider it a first marriage on its own terms if I got married again. I mean, I like the tradition."
"I'm very friendly with my first ex-wife. I would say that I'm on extremely good terms with the children I share with my second ex-wife," he explained.