The actress said she was "blackballed" by Hollywood for not playing according to the rules.
"How did the Oscar change my life? What it did was that it gave me a new reality. And it let me know that an award wasn't going to change my life - that I had to be in control of changing my life," she told the Hollywood Reporter.
The magazine had a special issue to celebrate the late Hattie McDaniel, who was the first African-American actor to win an Oscar for 1939 film 'Gone With the Wind'.
"(Like) Hattie said, 'After I won that award, it was as if I had done something wrong.' It was the same with me. I thought, once you won the award, that's the top prize - and so you're supposed to be treated as if you got the top prize.
Also Read
"(But) I got a phone call from Lee Daniels maybe six or seven months ago. And he said to me, 'Mo'Nique, you've been blackballed.' And I said, 'I've been blackballed? Why have I been blackballed?' And he said, 'Because you didn't play the game.' And I said, 'Well, what game is that?' And he gave me no response."
Daniels told the magazine that though Mo'Nique's demands through 'Precious' were not always in line with the campaign, she remained a friend.
"Mo'Nique is a creative force to be reckoned with. Her demands through 'Precious' were not always in line with the campaign. This soured her relationship with the Hollywood community. I consider her a friend. I have and will always think of her for parts that we can collaborate on.
"However, the consensus among the creative teams and powers thus far were to go another way with these roles," he said.