West, 37, made the point while addressing the students of the Oxford University Museum of Natural History, reported Aceshowbiz.
"One of my biggest Achilles heels has been my ego. And if I, Kanye West, the very person, can remove my ego, I think there's hope for everyone," he said.
West banned cell phones during his speech in order to stop students taking pictures of him, but some of them took it and posted it on Twitter.