Scientists from IIT Delhi have developed a silk-based hydrogel that emulates the process of hair growth, an advance that may help screen novel drugs for treating hair loss without using animal tests.
A study, published in the Journal of Cellular Physiology, shows how the three-dimensional mini organs can mimic the different stages of hair growth in humans.
Hair loss is a common ailment, and can be stressful for the people experiencing it. A number of factors including genes, illness, trauma and surgeries can lead to temporary or permanent hair loss.
However, alopecia - condition that occurs due to abnormal growth cycle or reduction in the size of hair follicles - is the major reason contributing to permanent hair loss, researchers said.
Numerous oils, creams, and medicines are commercially available but successful treatment of alopecia is still a far-fetched dream.
"The major reason for such inefficiency is there is no suitable human cell-based in vitro models available for drug testing. The currently available anti-alopecia drugs and cosmetics are tested on animals," said Sourabh Ghosh, an
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