The musician, 74, who performed with an 85-member symphony orchestra from Hungary and noted musicians from India, had a packed house with over 4000 people in the audience.
"I am very grateful and honoured to have the opportunity to entertain fans for the first time in Houston, I will be singing songs of the '70s to the current ones," he said at the beginning of the concert.
"I am the only composer in the world to have composed a song only in the ascending notes," he added.
Apart from Tamil, he has also worked in Malayalam, Telugu, Kannada and Hindi films as a music director.
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Raja was accompanied by noted south Indian singers K S Chitra, Mano, Haricharan, Rahul Nambiar, Sharath, Santosh and other Bollywood singers and mesmerizing members of Budapest symphony orchestra.
"We cannot thank Rajender Singh of Star Promotions, who has been bringing Bollywood shows nonstop for years, for bringing the legend finally to Houston and watching him live has been dream come true, an excited fan AnnaPoorani Roopa Balakrishnan said.
KS Chithra -- nightingale of Kerala -- charmed the audience with Ninnu Kori Varnam. As Mano started, the audience engulfed in a wave of nostalgia, cheered aloud for the bygone era.
In a career spanning over four decades, Raja has scored music for over 1,000 feature films. Altogether, 6,500 to 7,000 songs have been composed by him so far. He bagged five National Awards.
The musician will travel to other cities including, Dallas, San Jose, Chicago, Connecticut, and Toronto.