Lagarde said the US government's debt reduction plans are too abrupt, including the USD 85 billion in federal budget cuts known as the sequester. She said the current policies, if maintained, could lead to a contraction of 1.5 per cent in the US economy.
The US "should consolidate less in the short term, but give...Economic actors the certainty that there will be fiscal consolidation going forward," she said.
Lagarde had just begun speaking to students at the University of Amsterdam when the protesters began an organised, chanting disruption. One would call out "mic check!" and dozens more would yell back "Madame Lagarde!"
Security guards dragged students away until there were none left shouting, and eventually the interview resumed.
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Lagarde defended reforms the IMF had recommended be carried out in Greece, but admitted they had caused a greater economic decline than expected.
"What we underestimated is the consequences, that's clear," she said.
The 17-country eurozone is in recession, and Lagarde and an increasing number of economists now criticise a German-led drive for all members to get their budget deficits under 3 percent as soon as possible.
She praised a recent European Commission decision to allow France and the Netherlands more time to get their budget deficits down.
"The fact that they are allowing more time is a good move," she said.
One student attempted to pose a question out of turn later in her talk and guards began dragging him away. When he began questioning why Lagarde was only willing to field pre-approved questions, she intervened and asked him to be allowed to pose his question.
She said economic reforms work better in countries with less income inequality, and the IMF tries to include that in its advice which is not always heeded by governments.
"We're not imposing a particular system," she said, "We're trying to be rational about what can actually balance a country.