The event held on December 14 is a benefit for the Children's National Health System, reported Billboard.
Ora, 24, posted a photo of herself with Obama, his wife Michelle and daughters, Malia and Sashaon the stage in Instagram and captioned it, "Indescribable honour michelleobama."
"Ok I can't help it little sneak peak of my face before walking on the Obama stage. My legs were like jelly!! Thank you Audrey Hepburn for the inspiration!!," she added.
Other performers at the Christmas celebration included Darius Rucker, Christina Perri, Aloe Blacc and Earth, Wind & Fire.