After playing out a 1-1 draw with Philippines on Friday, India are still looking for their first international friendly win this year.
Last time the two teams met, Nepal edged past India 2-1 in Kathmandu.
Expecting a fierce challenge from the neighbours, national coach Wim Koevermans said his boys will go all out for a victory at the Kanchenjunga Stadium.
"It's not a match of revenge as is being stated. Every team takes the field to win. Sporting culture says that once you lose to a team you stay keen to win it the next time you play. We want to win. But it's not that easy. We know Nepal are a strong side," Koevermans said.
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"We are playing some good football and hope to carry on the trend," he added.
India skipper Sunil Chhetri feels their loss in the last meeting would have no impact in tomorrow's match.
"Tomorrow is a new game with both teams starting from the same score. History is there for stats," said Chhetri who is on the cusp of becoming the highest goal-scorer for India.
"To win matches you need to score. It just doesn't matter as long as we convert our chances. Whether it's me or anyone in the squad, it's immaterial as to who scores," Chhetri, who is presently tied with Bhaichung Bhutia on 42 goals, said.
"I'm very happy for him. I wish him all the luck," Koevermans stated.
"He is a strong character. It's such a wonderful news for Indian football," Chhetri said.