At number two, India will be the highest ranked side in the five-team tournament with 115 ratings points.
Apart from India, the tournament will feature fourth-ranked Sri Lanka, sixth-placed Pakistan, ninth-placed Bangladesh and unranked Afghanistan.
The side that finishes on top of the ODI rankings at the April 1 cut-off date receives a shield and a cheque of USD 175,000, while the side finishing second receives USD 75,000.
India held the number one rank for a year, but ceded the top position to Australia after losing their recent ODI series against New Zealand 0-4.
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Therefore, India can at best hope to retain the number two spot at the end of the Asia Cup, but their position could be challenged by fourth-ranked Sri Lanka.
Sri Lanka rounded off a three-match series against hosts Bangladesh with a six wickets win on Saturday to win the series 3-0. The clean sweep helped Sri Lanka gain a rating point to move to 109, at par with England, but when ratings were calculated beyond the decimal point, Angelo Mathews' men were able to move ahead into fourth place.
In such a scenario, Sri Lanka will gain three ratings points to finish on 112, a point ahead of India and therefore move up two places to second.
But if India win even one of their matches in Asia Cup, they will hold onto the number-two ranking, inspite of losing up to three ratings points to finish on 112.