India had last occupied the post from 1948 to 1968 but had not held it since then.
64-year-old Singh takes over from Samlee Plianbangchang of Thailand, who has served as regional director for 10 years now (two consecutive terms since 2004). She will hold the post for five years.
The delegates of 11 countries comprising WHO-SEAR region elected her at the 31st meeting of Health Ministers and 66th session of WHO Regional Committee for South-East Asia.
He said Singh is an acknowledged public health specialist and administrator with vast experience and recognition in public health and the UN system. She would be able to contribute to regional as well as global initiatives and further strengthen cooperation amongst SEAR Members States, Azad noted.
"I want to focus and improve upon the public health agenda in the region, which has changed rapidly over the last decade," Singh told PTI after being elected.