Ambassador Subrahmanyam Jaishankar said that India would see a decision to restrict certain temporary visas for skilled workers as a sign that the US economy is becoming less open for business.
"We think this is actually going to be harmful to us. It would be harmful to the American economy and, frankly, it would be harmful to the relationship" between the two countries, Jaishankar told AFP in an interview.
"Once I feel I'm not getting a fair deal, I am less responsive to the concerns of the other party. Then tomorrow if an American company comes and says, 'You know, we've got this set of problems,' the temptation for me is to say, 'I'm out for lunch,'" he said.
A version passed last year by the Senate, which is led by President Barack Obama's Democratic Party, offers automatic immigrant visas for foreigners who earn advanced science degrees at US universities. But it changes rules on so-called H-1B visas, which are issued to skilled workers who come temporarily to the United States.
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The Senate bill, while increasing the overall number of H-1B visas available, would hike fees and restrict additional H-1B visas for companies considered dependent on such foreign workers. The move came after complaints by US companies and labour groups that Indian tech firms bring in their own, lower-paid employees rather than hiring Americans.
The ambassador said he raised his concerns in meetings with more than 25 members of Congress, including House Speaker John Boehner and Senate Majority Leader Harry Reid, since he arrived in Washington in December.
Another prominent lawmaker, Senator Orrin Hatch, recently called India "the biggest battlefield" for intellectual property rights and accused the country of "rampant piracy and counterfeiting" to benefit its own industries.
Hatch made his remarks at the US Chamber of Commerce, which released a report that ranked India at the bottom of 25 countries in protection of intellectual property.