"Eight people including an Indian national was killed in Manang district while four foreigners were killed in Mustang district near Thorang Pass," according to officials.
Four Canadians, three Nepalis and one Indian national were killed in Manang district, 400 km north-west of Kathmandu, according to Trekking Agencies Association of Nepal (TAAN). Three Nepalese and one Israeli national were killed by the snow storm in Mustang.
The incident occurred in Thorang Pass area which lies between border of Manang and Mustang districts at an altitude of 5,416 metres.
There were 4 to 5 metre snow fall in the area, according to Gopal Babu Shrestha, Treasure of TAAN.
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"This was the worst incident in the mountain region of Nepal involving foreigners in the recent past," said Shrestha.
Some 85 foreign trekkers have lost contact with the staff of the trekking company in two separate places of Manang and Mustang districts.
The Nepal Army has said that it has rescued alive 18 foreign trekkers from Mustang area.
Many people might have been killed in the incident, according to unconfirmed sources.
A trekking agency staff quoting a rescued guide said that he had seen some 24-25 bodies lying in the snow.
In a separate incident, five foreign trekkers have gone missing from Dhaulagiri area, according to officials.
Nepal Army and Nepal Police personnel including local trekkers have been mobilised to carry out rescue works, he said.
Nepal Army has also launched aerial search through a helicopter in the snow storm hit area.
It was very difficult to establish communication with the missing trekkers and coordinate rescue due to heavy snow falls in the area.