An Infosys spokesperson confirmed David's exit from the company but didn't divulge details.
David is tipped to join Hewlett Packard Enterprise Co.
Infosys, which has been undergoing a turnaround under Sikka's leadership, has seen a string of senior leaders quitting the country's second largest IT firm.
Since Sikka took over as CEO in August 2014, many senior executives have left the company. These include high-profile names like chief financial officer Rajiv Bansal, head of manufacturing and EVP Sanjay Jalona, Infosys BPO head and EVP Gautam Thakkar and Infosys EdgeVerve head and EVP Michael Reh.