"That would be the only agreement that myself and President (Hassan) Rouhani will agree (to)," Zarif said during a joint news conference in Tehran with his Austrian counterpart Sebastian Kurz.
When asked whether hardliners could derail the nuclear talks, Zarif said: " Iran is not a monolith ... We will have those who will not favour an agreement, but at the end of the day what will count is the view of the majority of the Iranian people."
Tehran has been engaged in negotiations with the P5+1 -- Britain, China, France, Russia and the United States, plus Germany -- aimed at reaching a lasting accord on its nuclear ambitions.
Western nations and Israel have long suspected Iran of pursuing a nuclear weapons capability alongside its civilian programme, charges denied by Tehran.
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Any final deal with the West may involve Iran slashing its number of centrifuges, changing the design of a new reactor at Arak and giving UN inspectors more oversight.
At the news conference Zarif also rejected as "baseless" claims that Iran's ballistic missiles with a range of 2000 kilometres could carry nuclear warheads.
He said Iranian defence capabilities would not be discussed at the nuclear talks and reiterated that nuclear weapons contradicted Islamic teachings.
Kurz, meanwhile, said a comprehensive deal would help stabilise the region.
"One should avoid losing this opportunity, because this solution in regards with nuclear talks will lead to stability and security of the whole region ... And it will be helpful (from) the economic viewpoint for the Iranian people," Kurz said.