Foreign ministry spokeswoman Marzieh Afkham said Iran was "following up on reports regarding the possibility of two Iranian passengers aboard the plane."
"We are offering our cooperation to obtain more information," she said, pledging that Tehran would provide "any information on the Iranians and their status as soon as it is available."
Malaysian police said today that one of two suspect passengers aboard the missing jet was an Iranian illegal immigrant, as hopes for the 239 passengers and crew ebbed away.
One of the pair has been identified as 19-year-old Iranian Pouria Nour Mohammad Mehrdad, Malaysia's national police chief Khalid Abu Bakar told reporters.
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"We believe he is not likely to be a member of any terror group and we believe he was trying to migrate to Germany," Abu Bakar said, adding that authorities had not yet identified the other man.
Authorities have doubled the search radius to 100 nautical miles around the point where Malaysia Airlines MH370 disappeared from radar over the South China Sea early Saturday, en route from Kuala Lumpur to Beijing.