The Guard's website, as well as semi-official news agencies, reported the strikes today onDeirel-Zour, Syria.
The Guard's website said it launched surface-to-surface medium-range missiles targeting the area.
It did not immediately offer other specifics, other than to say the missiles were launched from Iran.
Such an attack is rare in Syria's long-running civil war, in which Iran is backing embattled Syrian President Bashar Assad.
Five Islamic State-linked attackers stormed Iran's parliament and a shrine to revolutionary leader Ayatollah Ruhollah Khomeini this month, killing at least 17 people and wounding more than 50.