Irani, who was recently shifted from the high-profile HRD portfolio, said that in the last five years as an MP, she has been "fortunate" to have got immense support from BJP leaders and people across the country.
The minister, who was elected five years ago, started a series of tweets but gave no indication what prompted her to take to the micro-blogging site on her tenure in the Rajya Sabha.
"It has been my privilege to have been able to reach out to the people of Anand & resolve their problems in whatever capacity I could," Irani wrote.
"I specially express my gratitude to people of Gujarat, particularly Anand which is my nodal district as Rajya Sabha MP from the state," she said.
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In the tweets, Irani shared snapshots of the welfare and civic work undertaken by her in Anand district during her tenure.
"Providing water and conserving the same along with ensuring clean surroundings has been the top priority in Anand," she tweeted.