Kassim Alhimidi, 49, was convicted of first-degree murder for killing 32-year-old Shaima Alawadi.
The jury had deliberated for a day and a half over its verdict.
Initially, police suspected the March 2012 killing was a hate crime after finding a note near the body saying: "This is my country. Go back to yours, terrorist."
But they subsequently alleged Alhimidi wrote it to confuse investigators.
Upon hearing the verdict, the couple's oldest son, Mohammed, stood up and screamed out profanities.
Prosecutors said Alhimidi killed his wife -- a mother of five -- by hitting her at least six times in the head with a blunt object as she sat at a computer.
Alhimidi said he was out at the time, but surveillance cameras and a neighbour contradicted his claim.
Alawadi was taken off life support three days after her teenage daughter found her unconscious in their home near San Diego following an "absolutely brutal beating."
Alhimidi claimed he was innocent, in an exchange in court in Arabic with the victim's mother.
His mother-in-law said she did not believe him.
"What I said in the courtroom is... If you killed her, you deserve to be killed, as well," she told reporters outside after the proceedings.
Alhimidi is due to be sentenced on May 15, and could face up to 26 years in prison.
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