ISIS operative Noureddine Chouchane alias Sabir, a Tunisian national and senior facilitator of the group in Libya, likely killed in the attack.
The US military conducted the air strike in Libya's Sabratha and destroyed an ISIS training camp. Chouchane was associated with the training camp which was wiped out in the air strike, Pentagon Press Secretary Peter Cook said.
"Destruction of the camp and Chouchane's removal will eliminate an experienced facilitator and is expected to have an immediate impact on ISIL's ability to facilitate its activities in Libya, including recruiting new ISIL members, establishing bases in Libya, and potentially planning external attacks on US interests in the region," Cook said.
Chouchane was also linked to June's hotel attack in Sousse, which killed 38 people, and the massacre that killed 22 people at the Bardo National Museum in Tunis.
"We are assessing the results of the operation and will provide additional information as and when appropriate," Cook said, adding the strike demonstrates the US will go after ISIS whenever it is necessary, using the full range of tools at our disposal.