The Syrian Observatory for Human Rights said three pro-regime militants were also killed repelling the attack on the village of Jub al-Jarah.
The Britain-based monitor said the attack on the village in the northeast of the province came early today, with violent clashes breaking out after the jihadists tried to storm the area.
"National Defence Forces and other pro-regime militias battled IS fighters with each side shelling the other," said the Observatory.
Jub al-Jarah lies northwest of the ancient city of Palmyra, which was captured by IS on May 21, and the group is also to the west of the village, in neighbouring Homs province.
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Its residents, like President Bashar al-Assad, mostly belong to the Alawite sect, an offshoot of Shiite Islam that IS considers heretical.
Two IS suicide bombers killed 10 Syrian soldiers yesterday in the northeastern city of Hasakeh.
"Ten soldiers were killed and 16 others injured in two suicide attacks carried out by IS against army positions in Hasakeh," the Observatory said.
A third suicide bomber hit a post manned by the Kurdish security forces in the city, causing serious damage to buildings in the area but no deaths.
Control of Hasakeh, which is ethnically mixed, is divided between Syrian troops and Kurdish forces.
On May 30, IS launched a bid to enter the city, but was pushed back after violent clashes with Syrian troops and Kurdish fighters.