Dozens of protesters gathered outside the Vatican's mission in Kuala Lumpur, the capital of Muslim-majority Malaysia, after prayers on Friday, urging the government to expel Archbishop Joseph Marino.
Marino, who arrived in Kuala Lumpur less than six months ago, recently elicited a rebuke from the government after he waded into a religious row over the right to translate "God" to "Allah" in Malay-language Bibles and other literature.
He was on Tuesday summoned to the foreign ministry over his remarks, and has since apologised.
It was not enough for some Muslim organisations in the country, however.
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"Joseph Marino is an enemy of the state. His actions have strained race relations in the country," said Ibrahim Ali, president of right-wing group Perkasa.
Ibrahim has previously drawn controversy by calling for the burning of the Bible.
"Marino must leave Malaysia," said Hasan Ali, the head of Islamic group JATI, who urged the government to close the mission and not to accept any envoy from the Vatican.
Yesterday, a Malaysian couple known for publishing a sexually explicit blog were charged with sedition and denied bail after they caused outrage with a prank Ramadan greeting on Facebook that showed them eating pork -- which is forbidden in Islam.
Malaysia has more than 2.5 million Christians in a population of 28 million, of which about 60 percent are Muslim.