"It is extremely shameful," Islamic scholar Maulana Sayed Ahmedalo Abidi, Imam-e-Juma Khoja Jama Masjid Dongri and Principal of Houza Ilmiya Najifi House, told reporters here.
"Shias are being attacked, shot and bombed. This is extremely serious," he said, urging the Indian government to take up the issue in international forums.
He also appealed to the government of Pakistan to ensure that Shias were protected from violence unleashed by militants.
"The Human Rights Commission of Pakistan must look into the issue," said Maulana Zaheer Abbas Rizvi, General Secretary All India Shia Muslim Personal Law Board.
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Pakistan has been besieged by militant attacks in recent years, many of them carried out by Pakistani Taliban, who have been waging a bloody insurgency against the government.
Radical Sunni militant groups have also increasingly targeted the country's Shias because they do not view them as real Muslims, Rizvi said in a statement.
The Islamic scholars also condemned the twin blasts at Hyderabad recently.