"What is happening in Egypt is the fall of what is known as political Islam," Assad said in an interview with Syrian state newspaper Ath-Thawra, excerpts of which were posted on the Internet.
"Anywhere in the world, whoever uses religion for political aims, or to benefit some and not others, will fall," Assad said.
Earlier today, Information Minister Omran al-Zohbi said Egyptian President Mohamed Morsi's departure is key to solving that country's crisis.
The Syrian branch of the Brotherhood today plays a key role in the exiled opposition National Coalition, which is recognised by more than 100 states and organisations as legitimate representative of the Syrian people.
Egypt is Sunni Muslim, as are the vast majority of rebels fighting to overthrow Assad whose Alawite sect is an offshoot of Shiite Islam.
Morsi last month announced severing ties with the Damascus regime and has repeatedly called on Assad to step down.