"Forces identified a suspect running towards an (army) post in Silwad, northeast of Ramallah," a spokeswoman said.
"The force shot the suspect, resulting in his death."
Silwad, close to the Jewish settlement of Ofra, is under constant stakeout by the Israeli army seeking to prevent attacks on passing settler traffic.
It is the scene of regular clashes between Palestinian stone throwers and troops.
A wave of violence since October has killed 222 Palestinians, 34 Israelis, two Americans, an Eritrean and a Sudanese, according to an AFP tally.
Others have been shot dead during protests and clashes with security forces.