The 'Titanic' actor Caprio will take on the 'Thor' lead Hemsworth, with Zac Efron and Sam Chaflin under the same category, reported People Magazine.
The four actors are battling it out against Jennifer Aniston, who stripped down for 'We're the Millers'.
The awards airing April 13 will be hosted by Conan O'Brien.
Nominees for best musical moment include Jennifer Lawrence in 'American Hustle' and Melissa McCarthy in 'Identity Thief'. Lawrence is also nominated for the best female performance as well as best kiss for her lip-lock with Amy Adams.