The 23-year-old singer was surrounded by questions about the track from his self-styled album 'Sign Of The Times' when he appeared for a radio interview, reported Billboard.
"I think it's pretty self-explanatory, right?" Styles told his friend Nick Grimshaw on BBC Radio 1 show with a sheepish grin.
When Grimshaw prodded him, Styles asked his manager, Jeffrey Azoff to rescue him.
"Help me, Jeffrey!" he said.
Although Styles did elaborate a little more, he neither confirmed nor denied the subject in the song was the "Blank Space" singer.