The stock lost 3.12 per cent to Rs 318.20 on the BSE.
At the NSE, it slipped 3.34 per cent to Rs 318.15.
The stock was the biggest loser among Sensex and Nifty scrips.
ITC on Friday reported a modest 3.65 per cent increase in standalone net profit at Rs 2,361.18 crore for the fourth quarter ended March 31, 2015 owing to muted growth in cigarette business and decline in agri segment revenue.
The Kolkata-headquartered firm had posted a net profit of Rs 2,278.01 crore in the January-March quarter of 2013-14.
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Revenue from the total FMCG business including cigarettes increased by 6 per cent to Rs 6,777.21 crore, from Rs 6,393.29 crore in the corresponding quarter in 2013-14.
During the quarter, revenue from cigarettes increased by 3.23 per cent to Rs 4,210.7 crore, from Rs 4,078.78 crore in the corresponding quarter in 2013-14.
Meanwhile, in the broader market, the BSE benchmark Sensex was trading at 27,827.17, down 130.33 points.