Nirmal Saund, 52, was jailed in February 2015 after being sentenced for conspiracy to produce drugs.
The West Midlands Police's Regional Crime Unit has now invoked the Proceeds of Crime Act (POCA) to initiate court action to regain some of his drugs empire cash.
At a court hearing on May 27, he was given three months to comply with the court order or face further jail time, the 'Birmingham Mail' reported.
Detective Constable Derek Tinsley said: "This was a sophisticated drugs network and officers carried out a lot of diligent work to identify cash which was put into multiple accounts.
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"We worked with a variety of law enforcement agencies internationally and this case should act as a warning; we will leave no stone unturned in making sure criminals do not prosper from their crimes."
The uncle-nephew duo were arrested after West Midlands Police watched some of their cannabis factories and dismantled their network of fake names, passports and utility bills.
As part of a wider crackdown on "dirty money", police have also taken action against another Indian-origin thief - Mann Singh Landa - who stole money from gaming machines.
The 42-year-old was told he must return 42,000 pounds or be jailed for a further two years.
Landa was sentenced to 20 months in January 2015 for the theft of 17,858 pounds from Pickwick Cricket Club in Moseley, near Birmingham.
A police investigation into his finances discovered further money which could not be accounted for and was found to be linked to criminal gains.