In an interview with The Hollywood Reporter Cameron reflected upon "Terminator" and the advances in artificial intelligence.
"Terminator" revolves around a cyborg assassin who is sent back in time from 2029 to 1984 to kill the woman whose son will one day become a Saviour against machines in a post- apocalyptic future.
Cameron has collaborated with "Deadpool" director Tim Miller to carry forward the franchise.
The director said he is often asked the question about man versus machines, a theme that is recurrent in his films.
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The filmmaker said while technology and humans were co- evolving, there might come a time when artificial intelligence will become too advanced for the human race.
"One of the scientists we met with recently, she said: 'I used to be really, really optimistic, but now I'm just scared.' Her position on it is probably that we can't control this. It has more to do with human nature.
Cameron said that like other previous inventions, artificial intelligence could be weaponised.
"And if you're doing it for business, you're doing it to improve your market share or whatever your business goals are. So you're essentially taking a machine smarter than a human and teaching it greed. Or it's for defense, in which case you're taking a machine smarter than a human and teaching it to kill. Neither one of those has a good outcome in my mind," he said.
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