In a video posted on her website, the 50-year-old diva said, they are in the process of officially ending their marriage.
"Yes, I'm separated from my husband. We're in court and the rest is in the god's hands," Jackson said.
The two got married in 2012 and share a son, Eissa Al Mana, together.
In the clip, she also confirmed her plans to resume the world tour she called off more than a year ago during her pregnancy with her son. Her comeback performance will be on September 7.
"I want to thank you guys for your patience for all your support throughout the years. Thank you so much, I cannot wait to see you guys," she said.