TV Asahi, which partially owns the rights to the character, has reached an agreement with Disney to air a version dubbed into English, said a spokeswoman with the Japanese broadcaster.
The cartoon has been broadcast in Japan for decades and has captivated children across Asia, but it will be his first foray in English into the American market, she said.
The US media giant is to air 26 episodes of the animation, amending storylines, character names and gadgets to suit US viewing tastes.
His magic pocket provides an endless supply of fantastical gadgets that help his young friend Nobita Nobi navigate the trials of everyday life.
Created by artist Fujiko F. Fujio, the character first appeared in manga strips in 1969, making the transition to small and big screen over the following decades.
Doraemon remains enormously popular in Japan, serving as an instantly recognisable cultural reference across generations.