The AIADMK supremo retained 13 of her ministers in her previous cabinet and inducted several new faces including four women.
Among those retained is Jayalalithaa's trusted lieutenant and party strongman of Theni district O Panneerselvam, who will again hold Finance portfolio. A key minister in the 2011-16 AIADMK tenure P Thangamani will be the Electricity Minister.
Salem district party veteran Eddapadi K Palaniswami, who was also a minister during 2011-16, will now man the key Public Works Department besides Highways and Minor Ports.
M C Sampath (Labour), R Kamaraj (Food and Civil Supplies), C Vijayabaskar (Health), S P Shanmuganathan (Milk dairy), R B Udhaya Kumar (Revenue), K T Rajenthra Balaji (Rural Industries), and K C Veeramani (Commercial Taxes).
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C V Shanmugam, who had a stint during 2011-16 and dropped later, has also found a place in the cabinet and would handle Law and Courts.
K P Anbazhagan who has been given the Higher Education portfolio was a minister in the AIADMK cabinet during 2003-06. D Jayakumar, the new Fisheries Minister, was the Speaker for a brief period during Jayalalithaa's previous tenure.
Four more new names, Nilofer Khafeel (Labour), Sevvoor S. Ramachandran (Hindu Religious and Charitable Endowments) G. Baskaran (Khadi and Village Industries Board), and P Balakrishna Reddy (Animal Husbandry), were announced later in the day.