"The train called AIADMK is now Fort St.George Express (state secretariat). You should make it reach the Red Fort," she told a meeting of party's Executive and General Council.
"In elections, our theme will be peace, prosperity and progress," the Chief Minister said at a packed marriage hall near here where the meeting was held.
This included the "struggles" in the Cauvery river water sharing issue, including getting the final award notified in the Central gazette, she said.
Tearing into the central government, she said it has to be "thrown out," and there was a need for a government that treated Tamil Nadu as a "partner" in national development and one that extends a hand of friendship.
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"This (UPA) is an anti-people government and the gifts it has given to the people of the country are unprecedented corruption, soaring inflation, family politics, threats from neighbours and repeated hike in prices of petrol and diesel," she said.
"A strong leadership is required at the Centre. A powerful central government will ensure that such issues do not arise," she said.
The present government was creating problems not only for Tamil Nadu but entire India she said, adding that the coming elections will ensure a change of guard in New Delhi.
"Only if AIADMK gets complete win (all 40 seats -39 in Tamil Nadu and one in Puducherry), can India's prosperity and security be ensured. So the party has to stand alone and win all 40 seats. That is our aim," she said.