The 30-year-old, who got engaged to Timerlake recently, said she does not want to play a couple on screen, reported Contactmusic.
"I think if it happens, it happens. We're definitely not searching for it, but if we can find something that's exciting for us both, then yeah. I mean, we want to be careful about playing a couple in a movie, I'm not sure about that, but playing enemies could be cool," she said.
Biel says being engaged to an actor makes it easier on their relationship.
"I think it is easier being engaged to a star because you understand what the other person is going through. You understand when they can't call because they are actually on set or whatever. But the schedules can be a nightmare," she said.