The 40-year-old beat out Don Cheadle, Louis CK, Alec Baldwin, Jason Bateman, and Matt LeBlanc for Best Actor in a Comedy Series.
After rattling off the names of his costars, family, and manager, Parsons gave one last shout-out to his love of more than 10 years, reported Us magazine.
"Thanks to my favourite person on the planet, Todd Spiewak," he said.
The three-time Emmy winner has been with Spiewak for more than a decade. He quietly came out as gay during an interview with the New York Times in May 2012.