Job burnout is a physical, cognitive, and emotional exhaustion that can result from stress at work.
In the study, those who were identified as being in the top 20 per cent of the burnout scale were found to have a 79 per cent increased risk of coronary heart disease (CHD), the buildup of plaque in the coronary arteries that leads to angina or heart attacks.
Dr Sharon Toker of Tel Aviv University's Faculty of Management and her fellow researchers found a link between job burnout and CHD.
Knowing that burnout has been associated with other cardiovascular risk factors, such as heightened amounts of cholesterol or fat in the bloodstream, the researchers hypothesised that it could also be a risk factor for coronary heart disease.
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Over the course of the study, a total of 8,838 apparently healthy employed men and women between the ages of 19 and 67 who presented for routine health examinations were followed for an average of 3.4 years.
During the follow-up period, 93 new cases of CHD were identified. Burnout was associated with a 40 per cent increased risk of developing CHD. But the 20 per cent of participants with the highest burnout scores had a 79 per cent increased risk.
Toker predicted that with a more extended follow-up period, the results would be even more dramatic.
Once burnout begins to develop, it sparks a downwards spiral and ultimately becomes a chronic condition, she warned.