The 53-year-old actor and the Paradis, 43, were together for 14 years before they separated in 2012, reported Aceshowbiz.
"Vanessa has been there for Johnny throughout the entire mess. We're all rooting for them to get back together! Lily probably blames Amber for breaking up her parents and she'd love for them to get back together - they both would," said Heather Rassel, who was once married to Depp's nephew.
The former couple have two children, daughter Lily-Rose Depp and son John Depp III together.
The 30-year-old actress filed for divorce in May this year and has accused Depp of abuse.
"We always suspected it was reverse psychology. Her pointing the finger at him for things that she did," Rassel said on the abuse claim.
Heard recently missed a deposition, after she was reported crying and screaming while refusing to testify under oath last weekend. She was scheduled to attend an emergency hearing on August 12, but couldn't make it.