Whedon, known for creating the TV shows "Buffy the Vampire Slayer" and "Agents of SHIELD", said the new comic book will be a "Victorian thriller", reported Entertainment weekly.
"It's a Victorian thriller about a meek chambermaid who is fed to a dark horror, but instead of dying, she returns, with knowledge, power, and rage she can neither deny nor control," Whedon said in a statement.
The comic, which will be launched as a six-issue mini-series, does not have a release date yet.