"We have cooperated fully with the European Commission throughout its five year investigation," the US bank said in a statement.
"We did not engage in any wrongdoing with respect to the EURIBOR benchmark. We will continue to vigorously defend our position against these allegations, including through possible appeals to the European courts."
The European Commission, the EU's executive arm, earlier Wednesday slapped huge fines on JPMorgan, HSBC and Credit Agricole for allegedly rigging the Euribor interest rate benchmark, which is used in a wide range of financial instruments.
The banks hit with the fines had rejected a 2013 settlement that the EU reached with Deutsche Bank, Societe Generale and Royal Bank of Scotland.