Juneja produced a sensational exhibition of strokeplay as he struck 16 fours and three sixes in his 50-ball knock to help Gujarat score 233 for three after they were put into bat in the Group A match at Emerald High School Ground.
Chasing the huge target, Kerala were bundled out for 143 in 19.1 overs.
With four points from today's match, Gujarat topped Group A and they face Punjab in the summit clash tomorrow. Punjab beat Uttar Pradesh by 51 runs in another match here today to top Group B.
But Juneja and Abdulahad Malik (84 not out)turned the match on its head with an unbroken partnership of 202 runs from 15.4 overs for the fourth wicket.
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Malik was no less aggressive than Juneja as his unbeaten 84 came from just 46 balls with the help of nine fours and three sixes.
The duo batted as if they were competing against each other in a contest of clearing the fence as the Kerala bowlers were sent for a leather hunt.
For Gujarat, pacer Mehul Patel and off-spinner Jesal Karia took three wickets each while Jasprit Bumrah and Rohit Dahiya chipped in with a wicket each.