The college is based in Ongole town, about 300km from here.
The 17-year-old girl lodged a complaint with Ongole police alleging repeated sexual assault by the official, Venkateshwarlu, over a period of time.
Based on the complaint, police filed a case against him under relevant sections of the Protection of Children from Sexual Offences Act (POCSO), Circle Inspector I Srinivasan said.
The girl has been sent for medical examination,he said, adding no arrest has been made so far.