The 21-year-old "Baby" hitmaker will be seen on the show on the mornings of September 3 and 4, followed by a musical performance on September 10, reported Entertainment Weekly.
The pop singer will also serve as a guest (musical and otherwise) on the September 2 episode of "The Tonight Show with Jimmy Fallon".
Bieber will croon "What Do You Mean?" for a non-NBC audience, and live for the first time, when he takes the stage Sunday at MTV's Video Music Awards.
"What Do You Mean?" is the lead single from Bieber's upcoming untitled album, the followup to 2012's "Believe".