The 44-year-old actor and comedian will play Dean Upton, the landlord of Rovers Return's rival pub the Flying Horse, reported Daily Mirror.
Dean will go head-to-head with Rovers Return landlord Steve McDonald (Simon Gregson) in a pub cricket match in scenes to be aired in August.
Speaking in a statement on 'Coronation Street's official website, Moorhouse said, "I'm delighted to be treading the cobbles.
"It's always been a dream of mine to appear in the Rovers Return, even though as Dean, landlord of the Flying Horse, I feel like I'm a spy!"