The 44-year-old actor, who is married to Jennifer Aniston, admitted he had to visit hospital after hurting himself while filming the three seasons of the show, reported Female First.
The Leftovers panel discussion during the 2016 Vulture Festival, he said: "I went to the hospital. I got 10 stitches in my lip and I broke my nose.
"Both episode eights in both seasons I shattered my hand, I got stitches in my head, and I broke my knuckles.