"It hasn't been a great week for dogs so with a heavy heart I must tell you, sweet Chester (aka Chedder cheese) has passed away," Cuoco, 30, captioned a photo of the small white puppy laying in the car.
The "Big Bang Theory" star explained that when she adopts dogs, she is not always aware of any health problems they may already have.
"We rescue these angels blindly and have no idea what problems they may have. I'm still in shock but I just keep feeling blessed to have him in my life even for a small amount of time.