The 36-year-old 'Stronger' hitmaker spoke at the Ivy League university as a part of his design company's DONDA Design Lecture series, reported Us magazine.
West, who talked about the design said, "Just wanted to tell you guys, I really do believe that the world can be saved through design, and everything needs to actually be 'architected.'
"And this is the reason why even some of the first DONDA employees were architects that started designing T-shirts instead of buildings. But just to see the work actually be actualised," he added.
West's fiance Kim Kardashian proudly watched as he addressed the audience members.
The 'Keeping Up with the Kardashians' star later shared a photo of the rapper on her Instagram page.
"My baby speaking at the Harvard Graduate School of Design," the 33-year-old reality star captioned the picture.