The former Grand Prix driver is looking forward to make a mark at the historic venue - where he qualified second last year - and establish himself as a consistent frontrunner in the fastest motor racing championship outside of Formula 1.
The 38-year-old had a mixed opening season with a sixth place finish at Fuji Speedway his best.
For the 2015 season, the series is scheduled to run eight rounds across Japan including yet another F1 venue with Okayama International Circuit joining Suzuka and Fuji Speedway. Okayama hosted two F1 races in 1994 and 1995 - both won by Michael Schumacher.
"I feel prepared to take on the challenge and it is still not going to be easy because once again the grid is extremely strong," the Tata backed driver added.
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The Indian will partner youngster Tomoki Nojiri at Team Dandelion Racing, switching from Team Impulm he competed with last year, with his best result being sixth place finish at Fuji Speedway.
Karthikeyan has already completed two pre-season tests with his new team and seems satisfied with the progress.
"Conditions were tough during both tests we had at Suzuka and Okayama, with low temperatures and rain often curtailing running but looking at the pecking order the car seems to have a good baseline to build on," he explained.
After being powered by naturally-aspirated V8 engines for well over a decade, Super Formula series switched to two-litre, 550bhp turbocharged engines in 2014 - in line with new turbo Formula 1 regulations which also came in force last year.