At the New York Fashion Week in September, the 33-year-old actress and fashion designer will present pieces from her label Holmes & Yang that she and her longtime friend and stylist Jeanne Yang formed in 2009, reported Women's Wear Daily.
The runway collection will show the Holmes & Yang Spring 2013 line and will be the label's first-ever appearance at the high-fashion, semiannual event.
It is unknown whether the partners will show at Mercedes-Benz Fashion Week hub Lincoln Center or elsewhere in the city.
Creating the lineup for the show will surely keep Holmes busy over the next few months and the star is not worried about falling into a dark place over her failed five-year marriage.
In a magazine interview weeks before she filed for divorce from Tom Cruise, Holmes said she is in a happy place and entering a new phase in life.
"I'm starting to come into my own. It's like a new phase." She is also set to star in a modern version of Anton Chekhov's play "The Seagull", and has shot the film "Molly", which she cowrote.