The 57-year-old actor, who once shared the mansion with ex-wife Camille, bought the Holmby Hills in 2007 for just under USD 8.75 million, reported Daily Express.
The seven-bedroom spread boasts a pool, wine cellar and library.
Grammar and his fourth wife, Kayte Walsh, recently purchased a six-bedroom home in Beverly Hills.
The couple hopes to use the new mansion as a family base when they welcome twins this summer.