The politically sensitive northern district of Kannur continued to be on top with 62.12% voting, the office of the Chief Electoral Officer said.
The state capital Thiruvananthapuram recorded the lowest of 44.93% till 3 p.m, it said.
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After a slow start with 12.11% till 9 a.m, the percentage picked up later in the day and touched 43.88% at 1 p.m.
Polling to decide the fate of 1,203 candidates in the fray was peaceful across the state so far, police said.
Tight security has been put in place across the state with the deployment of about 52,000 police personnel besides central forces.